PermeaDerm is a practical alternative to human cadaveric allograft for temporary wound coverage.1
Safe and effective for patients
Proven clinical performance as a temporizer.1 Mitigates concerns around cadaver skin disease transmission or cross-contamination.
Saves time for clinicians
No cold chain storage, thawing, or tissue tracking. PermeaDerm is easy to apply, transparent for at-a-glance wound assessment, and available in multiple sizes for a simplified workflow.1,2
Offers an economic advantage
Favorable pricing compared to a biologic (or other alternatives) with a dependable 5-year shelf life.3
The smarter alternative to allograft
A comparison chart of PermeaDerm versus allograft reveals several distinct advantages for clinicians and healthcare facilities.
| PERMEADERM | ALLOGRAFT | |
|---|---|---|
| Room Temperature Storage2,4 |  |  |
| Available in Large & Standardized Sizes2,1 | | |
| No Tissue Tracking4 | | |
| Wound Bed Visualization2,1 | | |
| Cost Advantage1,3 | | |
How does
PermeaDerm work?
Built as a dual-layer construct, PermeaDerm balances protection, permeability, and mobility.
- Outer silicone layer facilitates oxygen and moisture exchange while shielding against bacteria and external trauma
- Inner collagen- and aloe-biocoated nylon layer adheres gently to the wound bed, supporting early patient movement.
Together, these layers create an optimal environment for temporizing.
Real-world outcomes: Patient case
Early discharge and successful temporization with PermeaDerm
Following surgical debridement, PermeaDerm was applied to the wound as a temporizing agent.
Highlights:
- Patient was discharged on day 3, eliminating the need for prolonged hospitalization
- Evaluation on day 9 revealed successful formation of granulation tissue
- PermeaDerm was removed and a meshed split-thickness skin graft was applied for definitive wound closure
67-year-old female | Left hand, 2% TBSA treatment area
Case report courtesy of Dr. John Loftus (The Ohio State University, Wexner Medical Center).
mSTSG=meshed split-thickness skin graft
How to use PermeaDerm
Dressings for use with PermeaDerm
Wound assessment with PermeaDerm
Survey
0-3 Days
Ensure no fluid pockets or loose areas
- Fenestrate bubbles, seromas, hematomas, or roll out fluid
- Trim loose areas
- Place non-adherent to open areas
Color
3-5 Days
Color stabilizes | 3-5 days post-application
- Pink/red = vascular, healthy
- White/yellow/brown/grey = non-vascular, not healthy
Adherence
3-5 Days
Is the matrix
adhered?
- Non-adherence may indicate non-incorporation and non-viable tissue
- Infection concern: suggest using antimicrobials (wring-outs) or silver dressings
Next
3-7 Days
Discuss
surgical plan
- >1-week, hyper-adherence may occur and cause bleeding upon removal
- Re-excise as needed, apply autograft or reapply PermeaDerm if further temporary coverage required
The right size for the right wound.
PermeaDerm biosynthetic wound matrix is available in several sizes to meet wound management demands.
| Product | Part # | Units per Carton | CM2/UNIT (Per Carton) |
|---|---|---|---|
| PermeaDerm 5″ x 5″ | C2050500 | 10 sheets | 161 cm² (1,610 cm²) |
| PermeaDerm 5″ x 10″ | B1051000 | 8 sheets | 323 cm² (2,584 cm²) |
| PermeaDerm 10″ x 15″ | B2101500 | 3 sheets | 968 cm² (2,904 cm²) |
| PermeaDerm 15″ x 30″ | B4153000 | 1 sheet | 2,903 cm² (2,903 cm²) |
| PermeaDerm Glove XS | G1XS0000 | 2 gloves | 406 cm² (813 cm²) |
| PermeaDerm Glove S | G2S00000 | 2 gloves | 562 cm² (1,125 cm²) |
| PermeaDerm Glove M | G3M00000 | 2 gloves | 713 cm² (1,426 cm²) |
| PermeaDerm Glove L | G4L00000 | 2 gloves | 871 cm² (1,742 cm²) |
| PermeaDerm Glove XL | G5XL0000 | 2 gloves | 947 cm² (1,895 cm²) |
| PermeaDerm Glove XXL | G6XXL000 | 2 gloves | 1,024 cm² (2,048 cm²) |
Resources that support you and your patients
AVITA Medical is available to assist you with your coding and reimbursement questions. See our coding guide for information about coding for the use of PermeaDerm:
For general coding, coverage, and reimbursement questions that do not involve specific cases or patient health information, please e-mail us at: hema@avitamedical.com
For more in-depth support with benefits verification, prior authorization, appeals, or case-specific inquiries, please contact AVITA Patient Access Services at:
- E-mail: AVITA@alconj.org
- Phone: 1-866-965-3020
- Fax: 1-866-635-2270
- Akpunonu C, et al. J Surg. 2025;10(05):11308.
- Instructions for Use. PermeaDerm® Biosynthetic Wound Matrix.
- Internal pricing analysis data on file.2026.
- Association for Advancing Tissue and Biologics. Standards for tissue banking. Accessed 2026. https://www.aatb.org/ standards.