ReNovaCell™ is an innovative treatment that can be used in conjunction with conventional cosmetic and skin resurfacing procedures to restore pigmentation and improve the appearance of skin defects.

The technology behind ReNovaCell® enables a small sample of a patient’s own skin to be used to restore pigmentation1,2,3,4,5,6 and improve the appearance of scars1,2, sun-damaged skin, wrinkles and lesions associated with vitiligo and piebaldism – both conditions are characterised by patches of skin that have lost their normal pigment.

First of all a small sample of skin is collected from a healthy area of skin. While the clinician prepares the affected area to be treated, the ReNovaCell™ device is used to quickly prepare a suspension of healthy skin cells8 from the small skin sample, called Regenerative Epithelial Suspension™, or RES™. RES™, contains all the necessary elements9,10,11,12,13 for the promotion of healthy skin cell growth and regeneration14 and is easily applied by the clinician to the treatment area.

ReNovaCell™ has been safely used in thousands of procedures worldwide and offers distinct advantages for aesthetic procedures:

HOW IT WORKS

Simple. Safe. Effective.

A simple mechanism supported by robust clinical data, and safely used thousands of times.

Takes just 30 minutes to complete the following simple steps:


1

Take a small skin sample from a patient

2

Process in the ReNovaCell™ device

3

Apply the suspension back to the affected skin

4

Dress the treated area and let restoration complete


ADVANTAGES

ReNovaCell® offers distinct advantages for the restoration of skin pigmentation as a result of scarring or skin defects.
Avita’s ReNovaCell® unique proprietary technology enables a clinician to rapidly treat a patient using just a small sample of their own skin.  As well as being fast and simple to use, it is proven to be safe and effective.

  • Treatment forrestoration of pigmentation1,2,3,4,5,6
  • Improve the appearance of scar1,2
  • Enhance healing following resurfacing procedures1,7
  • Simple procedure performed in the clinic

Please enquire on availability in your country.

References
  1. Cervelli V, DeAngelis B, Spallone D, Lucarini L, Arpino A, and Balizani, A. “Use of a novel autologous cell-harvesting device to promote epithelialization and enhance appropriate pigmentation in scar reconstruction’. Clinical and Experimental Dermatology. 2009;35(7),776-780.
  2. K.H. Busch, R. Bender , N. Walezko, H. Aziz, M.A. Altintas , M.C. Aust. Combination of medical needling and non-cultured autologous skin cell transplantation (ReNovaCell) for repigmentation of hypopigmented burn scars. Burns. 2016 May 2. pii: S0305-4179(16)30072-9. doi: 10.1016/j.burns.2016.04.009. [Epub ahead of print]
  3. Kesting MR, MacIver C, Wales CJ, Wolff KD, Nobis CP, Rohleder NH. Surface-optimized free flaps for complex facial defects after skin cancer. J Craniomaxillofac Surg. 2015 Nov;43(9):1792-7. doi: 10.1016/j.jcms.2015.08.010. Epub 2015 Aug 20
  4. Hivelin M, MacIver C, Heusse JL, Atlan M, Lantieri L. Improving the colour match of free tissue transfers to the face with non-cultured autologous cellular spray–a case report on a chin reconstruction J Plast Reconstr Aesthet Surg. 2012 Aug;65(8):1103-6
  5. Cervelli V, Spallone D, Lucarini L, Palla L, Brinci L, and DeAngelis B. Treatment of stable vitiligo hands by ReCell system: preliminary report. European Review for Medical and Pharmacological Sciences. 2010;14(8):691-694
  6. Komen L, Vrijman C, Tjin EP, Krebbers G, de Rie MA, Luiten RM, van der Veen J4, Wolkerstorfer A. Autologous cell suspension transplantation using a cell extraction device in segmental vitiligo and piebaldism patients: A randomized controlled pilot study. J Am Acad Dermatol. 2015 Jul;73(1):170-2
  7. Dunne JA, Saleh DB, Rawlins JM. Management of rhinophyma with Versajet™ and ReCell®. Br J Oral Maxillofac Surg. 2013 Dec;51(8):e282-4. doi: 10.1016/j.bjoms.2013.02.009. Epub 2013 Mar 16.
  8. Wood FM, Giles N, Stevenson A, Rea S, ZFear M. Characterisation of the cell suspension harvested from the dermal epidermal junction using a ReCell® kit. Burns 2012; 38:44-51
  9. Zajicek R, Padcuga I, Suca H, Konigova R, Broz L, Matouskova E. Healing of widely mesh autografts using freshly isolated autologous epidermal cells and acellular Xe-Derma xenodermis. Healing Wounds 2012; 6 Singer AJ, Clark RAF. Cutaneous wound healing. New England Journal of Medicine 1999;341(10):738-746.
  10. Green H, Rheinwald JG, Sun T. Properties of an epithelial cell type in culture: the epidermal keratinocyte and its dependence on products of the fibroblast. Progress in Clinical and Biological research, 1977; 17:493-500.
  11. Rheinwald JG, Green H. Serial cultivation of strains of human epidermal keratinocytes: the formation of keratinizing colonies from single cells. Cell 1975; 6(3):331-343
  12. Pastar I, Stojadinovic O, Yin NC, Ramirez H, Nusbaum AG, Sawaya A, Patel SB, Khalid L, Isseroff RR, Tomic-Canic M. Epithelialization in wound healing: A comprehensive review. Advances in Wound Care 2014; 3(7):445-464
  13. Dunnill, C. and Georgopoulos, N. Personal communication 2016 University of Huddersfield (2):12-18
  14. Gilmore MA. Phases of wound healing. Dimens Oncol Nurs. 1991. 5(3):32-4