ReCell® is an innovative treatment for burns, also used in reconstructive procedures. ReCell® allows a clinician to collect specialised cells from a small sample of your skin and process them for application on another area that needs healthy skin cells, such as a burn.
While the clinician prepares the area to be treated, the collected cells are processed into RES™ (Regenerative Epithelial Suspension™), and are then sprayed onto your wound by the clinician.
RES™ can cover a wound many times the area of the donor site.
The ReCell® device processes your skin sample into RES™ (Regenerative Epithelial Suspension™). The device uses a proprietary enzyme formulation to process the skin cells. This enzyme formulation is used to disaggregate the cells into a solution – RES™, which is then applied to the wound to regenerate natural, healthy skin.
Burns generally heal with the growth of skin from the edges of a wound or by the formation of scar tissue (collagen) from within the wound itself. Research has shown that a wound that can heal itself in a short period (within 21 days) has less scarring than a wound that takes longer to heal.
The application of RES™ can reduce the time a wound takes to heal and therefore improve the quality of the skin.
The application of colour skin cells (melanocytes) may also result in more normal coloured skin.
When skin is taken to apply to other areas of damaged skin, the resulting wound (donor site) is painful and can be prone to infection and scarring.
The application of RES™ to a wound can reduce the time a wound takes to heal and therefore improve the quality of the skin.
Clinicians may recommend the use of ReCell® to reduce the risk of scar formation. The application of colour skin cells (melanocytes) may also result in more normal coloured skin.
A skin sample is a thin small shave of skin taken from an area of healthy normal skin. The sample is used to gather the cells that will be used to treat the wound. The size of the sample depends on the area that will be treated and will be calculated by your clinician.
The donor site is the area from which a skin sample is taken.
This generally occurs in an operating theatre under anaesthesia, although the option of local anaesthetic can be discussed with your clinician.
A small sample of skin is collected. The skin sample is usually around one to two centimetres square, but can be larger for larger treatments.
While the clinician is preparing the area to be treated by cleaning the wound, the healthy skin sample is placed into the ReCell® device. The ReCell® device separates the skin cells into a suspension, allowing the clinician to spray it onto the wound. The healthy cells are applied to the wound where they grow and reconstruct a skin that matches the surrounding tissue in terms of texture and colour.
The donor site is also treated with the spray to help it heal properly.
After the operation the treated area and donor site will be covered with a dressing. The area will initially be numb but may sting soon after the operation. This is normal and you are usually allowed to take medication to reduce any discomfort.
After about a week (depending on the reason why you had ReCell®) the dressing will be removed by your clinician. Your clinician will give you advice concerning what creams you are allowed to use, how much you can expose the treated area to the sun and what you should expect after the treatment.
ReCell® is a very safe procedure as it uses your own cells, so no specific risks are related to the procedure®. After removal of all the dressings, the skin will be red and there may be some scabs.
This is normal. Your clinician will give you advice concerning what creams you are allowed to use and what you should expect after the treatment.
As with any surgery, there are risks associated with ReCell® surgery. For example, you may have a reaction to the anaesthesia or you may get an infection that result in you requiring antibiotics, undergoing more surgery or getting scars. It is important that you discuss all possible outcomes with your clinician before consenting to any operation so that you are aware of all potential side effects and complications.
ReCell® should not be used on infected wounds. Patients with a known hypersensitivity (allergy) to anaesthesia, sodium lactate or the enzyme (Trypsin) should not be treated with ReCell®.
It is also important that the patient is willing to comply with post-operative instructions to avoid the risk of complications.